金美华,女,1973年,2007年博士毕业于韩国忠南大学,讲师,群众。先后主持过省部级及厅局级项目2项,指导校级大创1项。发表SCI论文五篇,授权国家发明专利2项,出版专著1部。主讲《神经生物学》、《细胞生物学》、《组织胚胎学》等课程。科研方向为过氧化物还原酶peroxiredoxin II 在氧化应激诱导的细胞损伤中的作用机制研究。
◆ 教研成果
(1)指导学生“双创”情况
贺鑫梅,大学生创新创业项目,Prx II 通过调节线粒体自噬抑制酒精诱导的肝细胞凋亡,XC2020015,英国365网站,2020.05-2021.05.
◆ 科研成果:
(1)项目及获奖
PrxII调控内质网线粒体互作保护海马线粒体氧化损伤的机制,(LH2023C076),黑龙江省科技厅,2023.07 – 2026.07,10.0万元,在研, 主持人
(2)论文及专著
Mei-Hua Jin, Lin Feng, Hong-Yi Xiang, Hu-Nan Sun, Ying-Hao Han and Taeho Kwon. Exploring the role of Prx II in mitigating endoplasmic reticulum stress and mitochondrial dysfunction in neurodegeneration. Cell Commun Signal. 2024 Apr 18;22(1):231.
Mei-Hua Jin, Nan-Nan Yu, Ying-Hua Jin, Ying-Ying Mao, Lin Feng, Yue Liu, Ai-Guo Wang, Hu-Nan Sun, Taeho Kwon, Ying-Hao Han. Peroxiredoxin II with dermal mesenchymal stem cells accelerates wound healing. Aging (Albany NY). 2021 May 24;13(10):13926-13940.
MeiHua Jin, DongQin Chen, YingHua Jin, YingHao Han, HuNan Sun and Taeho Kwon. Hispidin inhibits LPS-induced nitric oxide production in BV-2 microglial cells via ROS-dependent MAPK signaling. Exp Ther Med. 2021 Sep;22(3):970.
Mei-Hua Jin, Gui-Nan Shen, Ying-Hua Jin, Hu-Nan Sun, Xing Zhen, Yong-Qing Zhang, Dong-Seok Lee, Yu-Dong Cui, Li-Yun Yu, Ji-Su Kim, Taeho Kwon and Ying-Hao Han. Peroxiredoxin I deficiency increases pancreatic β‑cell apoptosis after streptozotocin stimulation via the AKT/GSK3β signaling pathway. Mol Med Rep. 2020 Sep;22(3):1831-1838.
Mei-Hua Jin, Jia-Bin Yu, Hu-Nan Sun, Ying-Hua Jin, Gui-Nan Shen, Cheng-Hao Jin, Yu-Dong Cui, Dong-Seok Lee, Sun-Uk Kim, Ji-Su Kim, Taeho Kwon, Ying-Hao Han. Peroxiredoxin II Maintains the Mitochondrial Membrane Potential against Alcohol-Induced Apoptosis in HT22 Cells. Antioxidants (Basel). 2019 Dec 18;9(1):1.
(3)发明专利
韩英浩,金美华,孙虎男. 一种脂肪干细胞介导的凝胶及其制备方法与应用. 专利号:ZL 2023 1 0865153.1。
孙虎男,金美华,韩英浩. 一种促进创面愈合的干细胞制剂及其制备方法. 专利号:ZL 2023 1 0864823.8。